Showing 1726-1740 of 2684
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High-throughput transcriptomic analysis of human primary hepatocyte spheroids exposed to per- and polyfluoroalkyl substances (PFAS) as a platform for relative potency characterization
Science
30 Mar 2021 | Toxicol Sci
The data indicate that PFOA, PFBS, PFOS, and PFDA may have common molecular targets and toxicities, but that PFOS and PFDS are the most similar.
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[Blog] Lowe’s bans PFAS in fabric protector sprays
News
29 Mar 2021 | NRDC Blog
As commitments to remove PFAS from products on store shelves gather steam, manufacturers should ensure that replacements are safe and should disclose all ingredients used in all fabric protectors they make.
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Per- and polyfluoroalkyl substances (PFASs) in Swedish household dust and exposure of pet cats
Science
29 Mar 2021 | Environ Sci Pollut Res Int
Dust was found to be a relevant exposure pathway for the ingestion of some PFAS for cats, and the serum levels of PFAS could be of relevance for the cat's health.
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Per- and polyfluoroalkyl mixtures toxicity assessment "Proof-of-Concept" illustration for the hazard index approach
Science
25 Mar 2021 | J Toxicol Environ Health A
Hazard index scores were used as an initial assessment of multiple health effects of fluorinated mixtures.
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Getting control of PMT and vPvM substances under REACH
Events
25 Mar 2021
This workshop will feature case studies of selected, emerging PMT/vPvM substances that are attracting increasing attention (e.g. ChemSEC's SIN List).
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UK ‘flying blind’ on levels of toxic chemicals in tap water
News
25 Mar 2021 | The Guardian
The UK government has so far only made plans to make plans to understand the levels of drinking water pollution.
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Prenatal exposure to mixtures of persistent endocrine-disrupting chemicals and birth size in a population-based cohort of British girls
Science
24 Mar 2021 | Epidemiology
PFAS was determined to be the most important contributor to the association with decreased birth weight.
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Norlite burned toxic AFFF in greater amounts – and longer – than previously thought, records show
News
23 Mar 2021 | Times Union
Because aqueous film forming foam, or AFFF, is not federally classified as a hazardous waste, there was no requirement that either the shipper – the Department of Defense – nor Norlite had to report its incineration.
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Fate and transport of per- and polyfluoroalkyl substances (PFASs) in the vadose zone
Science
23 Mar 2021 | Sci Total Environ
In this review, we critically discuss the current state of the knowledge and aim to interconnect the complex processes that control the fate and transport of PFASs in groundwater.
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Characterization of an AFFF impacted freshwater environment using total fluorine, extractable organofluorine and suspect per- and polyfluoroalkyl substance screening analysis
Science
23 Mar 2021 | Chemosphere
A tool was developed to close the organofluorine mass balance and to tentatively identify overlooked PFASs in various water sources.
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Perfluorooctanoic acid-induced immunotoxicity via NF-kappa B pathway in zebrafish (Danio rerio) kidney
Science
23 Mar 2021 | Fish Shellfish Immunol
This study expands the understanding of PFOA-induced immunosuppression and suggests that toxicity mechanisms should be considered for further health risk assessment of emerging pollutants.
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Plasma Concentrations of Per- and Polyfluoroalkyl Substances and Body Composition from Mid-childhood to Early Adolescence
Science
23 Mar 2021 | J Clin Endocrinol Metab
Early-life exposure to some but not all PFAS may be associated with adverse changes in body fat levels.
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Sediment quality assessment framework for per- and polyfluoroalkyl substances: results from a preparatory study and REGULATORY IMPLICATIONS
Science
23 Mar 2021 | Integr Environ Assess Manag
PFOS is a suitable indicator of PFAS contamination in sediments from small streams, being the most detected and on average with the highest concentrations among the analyzed PFAS in Switzerland.
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Development of a Gestational and Lactational Physiologically Based Pharmacokinetic (PBPK) Model for Perfluorooctane Sulfonate (PFOS) in Rats and Humans and Its Implications in the Derivation of Health-Based Toxicity Values
Science
23 Mar 2021 | Environ Health Perspect
This study provides a quantitative tool to aid risk reevaluation of PFOS, especially in sensitive human subpopulations, and it provides a basis for extrapolating to other PFAS.
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N-acetyl cysteine co-treatment abates perfluorooctanoic acid-induced reproductive toxicity in male rats
Science
23 Mar 2021 | Andrologia
N-acetylcysteine suppressed inflammatory responses and remedied PFOA-mediated reproductive injuries in rats.