Showing 511-525 of 529
-
Computational systems biology as an animal-free approach to characterize toxicological effects of persistent organic pollutants
Science
3 Feb 2020 | ALTEX
Researchers used computers to predict the toxicity of persistent organic pollutants such as PFAS.
-
‘Our voices are not being heard’: Colorado town a test case for California PFAS victims
News
31 Jan 2020 | Los Angeles Times
When Wendy Rash was diagnosed in 2005 with a thyroid disorder, chronic fatigue and other ailments, her doctor couldn’t explain her suddenly failing health. It wasn’t until 2016 that scientists tested the tap water they had been drinking and found it was contaminated with man-made chemicals known as per-fluorinated compounds.
-
Immunotoxicity and allergenic potential induced by topical application of perfluorooctanoic acid (PFOA) in a murine model
Science
16 Jan 2020 | Food Chem. Toxicol.
PFOA was found to be toxic to the immune system through skin exposure.
-
The emerging PFOS alternative OBS exposure induced gut microbiota dysbiosis and hepatic metabolism disorder in adult zebrafish
Science
16 Jan 2020 | Comp. Biochem. Physiol. C Toxicol. Pharmacol.
The PFAS alternative, sodium ρ-perfluorous nonenoxybenzene sulfonate, was found to change gut bacteria levels and negatively impact metabolism.
-
Prenatal exposure to perfluorodecanoic acid is associated with lower circulating concentration of adrenal steroid metabolites during mini puberty in human female infants. The Odense Child Cohort
Science
13 Jan 2020 | Environ. Res.
High prenatal exposure to PFDA associated with decreased hormone production in babies.
-
Quantitative bias analysis of the association between subclinical thyroid disease and two perfluoroalkyl substances in a single study
Science
25 Dec 2019 | Environ. Res.
A physiologically based pharmacokinetic model was used to quantify bias in a reported PFAS-thyroid association.
-
Altered expression and activity of phase I and II biotransformation enzymes in human liver cells by perfluorooctanoate (PFOA) and perfluorooctane sulfonate (PFOS)
Science
10 Dec 2019 | Toxicology
PFOA and PFOS found to inhibit the body's ability to breakdown and absorb nutrients.
-
Topic of Cancer: How PFAS threaten our water
News
10 Dec 2019 | Capital & Main
What’s more, while the persistent and mobile nature of PFAS chemicals means that no neighborhood is safe from contamination, smaller water systems—particularly those serving disadvantaged communities—face an uphill task in tackling the problem due to the higher probability of aging infrastructure and limited resources, as compared to larger utilities.
-
Top U.S. toxicologist was barred from saying PFAS cause disease in humans. She’s saying it now
News
24 Oct 2019 | The Intercept
“I was banned from doing it,” said Birnbaum. “I had to use ‘association’ all the time. If I was talking about human data or impacts on people, I had to always say there was an association with a laundry list of effects.”
-
Temporal Trends (1981-2013) of per- and polyfluoroalkyl substances and total fluorine in Baltic cod (Gadus morhua)
Science
22 Oct 2019 | Environ. Toxicol. Chem.
Decrease body length was associated with PFDoDA and FOSA exposure.
-
Perfluoroalkyl substances and bone health in young men: a pilot study.
Science
8 Oct 2019 | Endocrine
Exposure to PFAS may lead to an increased risk of developing osteoporosis.
-
Association between perfluoroalkyl substance exposure and thyroid hormone/thyroid antibody levels in maternal and cord blood: The Hokkaido Study
Science
16 Sep 2019 | Environ Int
Hormone function disrupted by the presence of PFAS in a cohort of 701 mother‑neonate pairs.
-
Human-Based Exposure Levels of Perfluoroalkyl Acids May Induce Harmful Effects to Health by Disrupting Major Components Androgen Receptor Signalling In Vitro
Science
27 Aug 2019 | Exp. & Health
Certain PFAS found to disrupt multiple parts of the human endocrine system.
-
Maternal Plasma per- and Polyfluoroalkyl Substance Concentrations in Early Pregnancy and Maternal and Neonatal Thyroid Function in a Prospective Birth Cohort: Project Viva (USA)
Science
8 Jul 2019 | Environmental Health Perspectives
Prenatal exposure to PFAS negatively influences thyroid function in both mothers and infants.
-
Prenatal exposure to perfluoroalkyl substances, immune-related outcomes, and lung function in children from a Spanish birth cohort study
Science
28 Jun 2019 | Int J Hyg Environ Health
Exposure to PFOA linked to reduced lung function in young children.