Showing 61-75 of 150
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Enhancing Scientific Support for the Stockholm Convention’s Implementation: An Analysis of Policy Needs for Scientific Evidence
Science
21 Feb 2022 | ES&T
Scientists discuss the success of the Stockholm Convention for addressing global threats of PFAS and provide guidance for further support of the Convention.
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Risk of Cancer in a Community Exposed to Per- and Poly-Fluoroalkyl Substances
Science
20 Feb 2022 | Environ Health Insights
Merrimack residents experienced a significantly higher risk of at least 4 types of cancer between 2005 and 2014 which may be linked to PFAS-contaminated drinking water.
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Firefighters’ Catch-22: Protective gear full of carcinogens
News
16 Feb 2022 | E&E News
Firefighters are exposed to cancer-causing chemicals in the very clothing and gear that is meant to protect them, a paradox that stems from standards set under industry influence.
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US EPA sued over gaps in PFAS release reporting
News
21 Jan 2022 | C&EN
Advocacy groups are asking a federal court to force the US Environmental Protection Agency to plug what they call loopholes in two rules on reporting releases of dozens of toxic, highly persistent chemicals.
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The comprehensive analysis based study of perfluorinated compounds-Environmental explanation of bladder cancer progression
Science
20 Dec 2021 | Ecotoxicol Environ Saf
PFAS could promote bladder cancer progression.
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The use of in vitro methods in assessing human health risks associated with short-chain perfluoroalkyl and polyfluoroalkyl substances (PFAS)
Science
13 Dec 2021 | J Appl Toxicol
This review summarizes the PFAS toxicity data obtained using human cells in vitro, discusses the advantages and limitations of cell-based models, and provides thoughts on potential solutions to the challenges of these methods.
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Tumor and serum levels of per- and polyfluoroalkyl (PFAS) in hepatobiliary and gastrointestinal malignancy
Science
30 Nov 2021 | Am J Surg
Cancer patients had higher levels of PFOS than the national average and those with higher blood serum levels of PFOS were more likely to have higher levels of PFOS in tumors.
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Per- and Poly-fluoroalkyl Substances (PFAS) and Female Reproductive Outcomes: PFAS Elimination, Endocrine-Mediated Effects, and Disease
Science
30 Nov 2021 | Toxicology
A summary of the role of PFAS in female reproductive dysfunction and disease is presented with the major data gaps, highlighting the importance for further study of the action mechanisms of PFAS harm in women.
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Two ‘Forever Chemicals’ More Toxic Than Previously Thought: EPA Drafts
News
18 Nov 2021 | The Hill
The agency also found that PFOA is “likely” carcinogenic to humans.
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[Blog] The Big Reveal: Hundreds of Health Studies on Next Gen PFAS
News
10 Nov 2021 | NRDC
The PFAS-Tox Database has been updated and includes 1068 studies.
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Per- and Polyfluoroalkyl Substance Exposure Combined with High-Fat Diet Supports Prostate Cancer Progression
Science
9 Nov 2021 | Nutrients
PFOS exposure in conjunction with a high-fat diet may contribute to prostate cancer development and increase tumor aggressiveness.
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Perfluorooctane sulfonate (PFOS) triggers migration and invasion of esophageal squamous cell carcinoma cells via regulation of Zeb1
Science
9 Nov 2021 | Drug Chem Toxicol
Environmental exposure and body accumulation of PFOS might be an important risk factor for esophagus cancer progression, one of the most deadly cancers worldwide.
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Per- and polyfluoroalkyl substances, epigenetic age and DNA methylation: a cross-sectional study of firefighters
Science
2 Nov 2021 | Epigenomics
PFAS exposure was associated with indicators of adverse health outcomes in firefighters.
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Cancer incidence in a Swedish cohort with high exposure to perfluoroalkyl substances in drinking water
Science
26 Oct 2021 | Environ Res
Analysis of a large cohort exposed to high levels of PFAS, dominated by PFHxS and PFOS, revealed a moderately increased risk of kidney cancer.
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Application of a Framework for Grouping and Mixtures Toxicity Assessment of PFAS: A Closer Examination of Dose-Additivity Approaches
Science
21 Oct 2021 | SOT
This article presents a new and systematic analysis of available PFAS toxicity study data using a tiered mixtures risk assessment framework consistent with the United States and international mixtures guidance.