Showing 1006-1020 of 1708
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Emerging investigator series: human CYP2A6 catalyzes the oxidation of 6:2 fluorotelomer alcohol
Science
9 Nov 2021 | Environ Sci Process Impacts
An enzyme was found to play an important role in the indirect human exposure to bioactive and persistent PFCAs which are metabolites of 6:2 fluorotelomer alcohol.
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Half-lives of several polyfluoroalkyl substances (PFAS) in cattle serum and tissues
Science
9 Nov 2021 | Food Addit Contam Part A Chem Anal Control Expo Risk Assess
Cattle drank water contaminated with PFAS-containing fire fighting from were found to have PFOS, PFHpS, PFNA, PFDA, and PFHxS in their blood which was used to estimate half-lives for these substances.
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Per- and polyfluoroalkyl substance (PFAS) exposure, maternal metabolomic perturbation, and fetal growth in African American women: A meet-in-the-middle approach
Science
9 Nov 2021 | Environ Int
Higher PFOA and PFNA blood levels in pregnant African American women were associated with reduced fetal growth.
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Engineering human liver fatty acid binding protein for detection of poly- and perfluoroalkyl substances
Science
9 Nov 2021 | Biotechnol Bioeng
A novel method of detecting selected PFAS in water (at parts per billion or million levels) by using human liver proteins was developed and implemented in field applications.
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Global occurrence and probabilistic environmental health hazard assessment of per- and polyfluoroalkyl substances (PFASs) in groundwater and surface waters
Science
8 Nov 2021 | Sci Total Environ
US EPA drinking water lifetime health advisory levels were exceeded for PFOS in up to 74% of Oceania groundwater samples and exceeded for PFOA in up to 69% of North American groundwater samples.
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Millions consuming 'invisible toxic cocktail' of cancer-linked chemicals: study
News
3 Nov 2021 | The Hill
Millions of Americans are unknowingly ingesting water that includes “an invisible toxic cocktail” of cancer-linked chemicals, a new survey of the nation’s tap water has found.
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Michigan to stop buying most products made with PFAS chemicals
Policy
2 Nov 2021
The Michigan Department of Technology, Management and Budget must “incentivize suppliers to offer products that do not contain intentionally added PFAS by seeking to purchase such products where possible."
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Identification of point source dischargers of per- and polyfluoroalkyl substances in the United States
Science
2 Nov 2021 | AWWA
A screening-level analysis was conducted of the potential for environmental PFAS releases from contaminated sites, active industrial sites, wastewater treatment plants, and waste disposal sites nationwide.
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Bioaccumulation and metabolic response of PFAS mixtures in wild-caught freshwater turtles (Emydura macquarii signata) using omics-based ecosurveillance techniques
Science
2 Nov 2021 | Sci Total Environ
Turtle populations were surveyed to understand the effects of PFAS exposure around factories.
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Per- and polyfluoroalkyl substances, epigenetic age and DNA methylation: a cross-sectional study of firefighters
Science
2 Nov 2021 | Epigenomics
PFAS exposure was associated with indicators of adverse health outcomes in firefighters.
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Analytical uncertainties in a longitudinal study - A case study assessing serum levels of per- and poly-fluoroalkyl substances (PFAS)
Science
2 Nov 2021 | Int J Hyg Environ Health
The variance between sample collection was found to be an important consideration affecting long-term PFAS studies.
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Chronic exposure to perfluorohexane sulfonate leads to a reproduction deficit by suppressing hypothalamic kisspeptin expression in mice
Science
2 Nov 2021 | J Ovarian Res
Long-term exposure of mice to PFHxS reduced reproductive ability by inhibiting normal organ development.
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Perfluoroalkyl substances exposure and immunity, allergic response, infection, and asthma in children: review of epidemiologic studies
Science
1 Nov 2021 | Heliyon
Immunosuppression, diminished vaccine efficacy, and increased risk of infections were found following, infant, and early childhood PFAS exposures.
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Exposure to environmental contaminants is associated with altered hepatic lipid metabolism in non-alcoholic fatty liver disease
Science
27 Oct 2021 | J Hepatol
PFAS was found to disrupt liver function in women to a greater extent than men.
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Cancer incidence in a Swedish cohort with high exposure to perfluoroalkyl substances in drinking water
Science
26 Oct 2021 | Environ Res
Analysis of a large cohort exposed to high levels of PFAS, dominated by PFHxS and PFOS, revealed a moderately increased risk of kidney cancer.